甲苯 · 英文 MSDS

CAS：108-88-3

Safety Data Sheet

Product name: TolueneCAS No.: 108-88-3

Prepared in accordance with GB/T 16483, GB/T 17519

SECTION 1: Identification of the substance/mixture and of the company/undertaking

>Product identifier

Product name: Toluene
CBnumber: CB4233905
CAS: 108-88-3
EINECS Number: 203-625-9
Synonyms: Toluene,tol

>Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

>Company Identification

Company: Linyi Tuohui New Materials Co., Ltd.
Address: Room A6159, 6F, Building 1, Linyi Software Park, No.6 Yihe Road, Zhimadun Subdistrict, Yishui New Area, Linyi City, Shandong Province, China
Telephone: +86 176 6460 5089 (Manager Niu) / +86 130 4664 1786 (Manager Li)
Email: nathan@tuohui-chem.com
WhatsApp: +86 176 6460 5089
Emergency telephone: +86 176 6460 5089

SECTION 2: Hazards identification

>GHS Label elements, including precautionary statements

Symbol(GHS)

Signal wordDanger

Precautionary statements

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P405 Store locked up.

Hazard statements

H225 Highly Flammable liquid and vapour

H302 Harmful if swallowed

H304 May be fatal if swallowed and enters airways

H315 Causes skin irritation

H333 May be harmful if inhaled

H336 May cause drowsiness or dizziness

H361 Suspected of damaging fertility or the unborn child

H373 May cause damage to organs through prolonged or repeated exposure

Disposal

WARNING.Cancer - https://oehha.ca.gov/proposition-65/chemicals/toluene

SECTION 3: Composition/information on ingredients

>Substance

Product name: Toluene
Synonyms: Toluene,tol
CAS: 108-88-3
EC number: 203-625-9
MF: C7H8
MW: 92.14

SECTION 4: First aid measures

>Description of first aid measures

General advice

Show this material safety data sheet to the doctor in attendance.

If inhaled

After inhalation: fresh air. Call in physician.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

In case of eye contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

If swallowed

After swallowing: caution if victim vomits. Risk of aspiration! Keep airways free. Pulmonary failure possible after aspiration of vomit. Call a physician immediately.

>Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

>Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

>Extinguishing media

Suitable extinguishing media

Carbon dioxide (CO2) Foam Dry powder

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

>Special hazards arising from the substance or mixture

Carbon oxides Combustible.

Pay attention to flashback.

Vapors are heavier than air and may spread along floors.

Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.

>Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

>Further information

Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.

>NFPA 704

SECTION 6: Accidental release measures

>Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.

Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.

>Environmental precautions

Do not let product enter drains. Risk of explosion.

>Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.

Chemizorb). Dispose of properly. Clean up affected area.

>Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

>Precautions for safe handling

> Advice on safe handling

Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.

> Advice on protection against fire and explosion

Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.

> Hygiene measures

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

For precautions see section 2.2.

>Conditions for safe storage, including any incompatibilities

> Storage conditions

Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.

Handle and store under inert gas.

>Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

>control parameter

Hazard composition and occupational exposure limits

Does not contain substances with occupational exposure limits.

>Exposure controls

Personal protective equipment

Eye/face protection

Use equipment for eye protection tested and approved under appropriate

government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Skin protection

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Full contact Material: Viton

Minimum layer thickness: 0,7 mm Break through time: 480 min

Material tested:Vitoject (KCL 890 / Aldrich Z677698, Size M)

Splash contact Material: Viton

Minimum layer thickness: 0,7 mm Break through time: 480 min

Material tested:Vitoject (KCL 890 / Aldrich Z677698, Size M)

Body Protection

Flame retardant antistatic protective clothing.

Respiratory protection

Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds

The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.

These measures have to be properly documented.

Control of environmental exposure

Do not let product enter drains. Risk of explosion.

Exposure limits

TLV-TWA 100 ppm (～375 mg/m³) (ACGIH, NIOSH, and MSHA), 200 ppm (～750 mg/ m3) OSHA; ceiling 300 ppm, peak 500 ppm/ 15 min (OSHA); STEL 150 ppm (ACGIH).

SECTION 9: Physical and chemical properties

>Information on basic physicochemical properties

Appearance liquid
Odourbenzene-like
Odour Threshold0,2 ppm
pHNot applicable
Melting point/freezing pointMelting point/range: -93 °C
Initial boiling point and boiling range110 - 111 °C
Flash point4,0 °C - c.c.
Evaporation rateNo data available
Flammability (solid, gas)No data available
Upper/lower flammability or explosive limits Upper explosion limit: 7,1 %(V) Lower explosion limit: 1,2 %(V)
Vapour pressure 30,88 hPa at 21,1 °C
Vapour density 3,18
Relative density0.865～0.870(20/20℃)(Ph.Eur.)
Water solubility0,58 g/l at 25 °C - partly soluble
Partition coefficient: n-octanol/waterlog Pow: 2,73 at 20 °C - Bioaccumulation is not expected.
Autoignition temperature 535,0 °C
Decomposition temperature No data available
ViscosityViscosity, kinematic: No data available Viscosity, dynamic: 0,56 mPa.s at 25 °C
Explosive propertiesNo data available
Oxidizing propertiesNo data available
Henry's Law Constant1.05 at 40 °C, 1.68 at 50 °C, 2.62 at 60 °C, 3.15 at 70 °C, 3.97 at 80 °C (headspace-GC, Vane et al., 2001)

>Other safety information

Conductivity < 0,01 μS/cm

Surface tension 27,73 mN/m at 0,516g/l at 25 °C

Relative vapor density

3,18

SECTION 10: Stability and reactivity

>Reactivity

Vapors may form explosive mixture with air. Vapors may form explosive mixture with air.

>Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) . The product is chemically stable under standard ambient conditions (room temperature) .

>Possibility of hazardous reactions

Risk of explosion with: fuming sulfuric acid Nitric acid

silver perchlorates nitrogen dioxide

nonmetallic halides acetic acid

halogen-halogen compounds uranium hexafluoride organic nitro compounds

Violent reactions possible with: Strong acids

Strong oxidizing agents sulfur

with Heat.

>Conditions to avoid

Warming. Warming.

>Incompatible materials

rubber, various plastics

>Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

>Information on toxicological effects

Acute toxicity

LD50 Oral - Rat - male - 5.580 mg/kg
(Tested according to Directive 92/69/EEC.)
LC50 Inhalation - Rat - male and female - 4 h - 25,7 mg/l (OECD Test Guideline 403)
LD50 Dermal - Rabbit - > 5.000 mg/kg Remarks: (ECHA)

Skin corrosion/irritation

Skin - Rabbit
Result: irritating - 4 h Remarks: (ECHA)

Serious eye damage/eye irritation

Eyes - Rabbit
Result: slight irritation (OECD Test Guideline 405)

Respiratory or skin sensitization

(Regulation (EC) No. 440/2008, Annex, B.6)

Germ cell mutagenicity

Test Type: In vitro mammalian cell gene mutation test Test system: Mouse lymphoma test
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476
Result: negative
Test Type: Ames test
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: Mutagenicity (Salmonella typhimurium - reverse mutation assay) Result: negative
Test Type: Chromosome aberration test Species: Rat
Cell type: Bone marrow Application Route: i.p.
Result: negative Remarks: (ECHA)

Carcinogenicity

No data available

Reproductive toxicity

Suspected of damaging the unborn child.

Specific target organ toxicity - single exposure

May cause drowsiness or dizziness. - Central nervous system

Specific target organ toxicity - repeated exposure

May cause damage to organs through prolonged or repeated exposure. - Central nervous system

Aspiration hazard

Aspiration hazard, Aspiration may cause pulmonary edema and pneumonitis.

Toxicity

LD50 orally in rats: 7.53 g/kg (Smyth)

SECTION 12: Ecological information

>Toxicity

Toxicity to fish

flow-through test LC50 - Oncorhynchus kisutch (coho salmon) - 5,5 mg/l - 96 h

Remarks: (ECHA)

Toxicity to daphnia and other aquatic invertebrates

EC50 - Ceriodaphnia dubia (water flea) - 3,78 mg/l - 48 h (US-EPA)

Toxicity to bacteria

static test EC50 - Bacteria - 84 mg/l - 24 h

Remarks: (ECHA)

>Persistence and degradability

Biodegradability aerobic - Exposure time 20 d

Result: 86 % - Readily biodegradable. Remarks: (IUCLID)

>Bioaccumulative potential

Bioaccumulation Leuciscus idus (Golden orfe) - 3 d

- 0,05 mg/l(Toluene)

Bioconcentration factor (BCF): 90

>Mobility in soil

No data available

>Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

>Toxics Screening Level

The initial threshold screening level (ITSL) for toluene is 5,000 μg/m3 based on a 24-hour averaging time.

>Other adverse effects

No data available

SECTION 13: Disposal considerations

>Waste treatment methods

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Violent reaction with mixtures of nitric and sulfuric acid.

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.

SECTION 14: Transport information

>UN number

ADR/RID: 1294 IMDG: 1294

SECTION 15: Regulatory information

>Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals

China Catalog of Hazardous chemicals 2015:Listed. website: https://www.mem.gov.cn/

Measures for Environmental Management of New Chemical Substances

Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/

United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/

European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/

Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: https://emb.gov.ph/

EC Inventory:Listed.

Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/

New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/

Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr

SECTION 16: Other information

>Abbreviations and acronyms

CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short term exposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%

>References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

>Other Information

Depending on the degree of exposure, periodic medical examination is suggested.Use of alcoholic beverages enhances the harmful effect.

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